ESPCI web site
ESPCI Paris - PSL
ESPCI Paris - PSL is a major institution of higher education (a French "Grande École d’ingénieurs"), an internationally renowned research center (6 Nobel Prizes), and a fertile ground of innovation for industry (3 start-ups created/year). ESPCI is a highly multidisciplinary environment with teaching and research in physics, chemistry and biology.
Prof. Andrew Griffiths’ Lab
The research activities of the Team of Biochemistry, directed by Prof. Andrew GRIFFITHS, are based around droplet-based microfluidics, a powerful new ultrahigh-throughput system in which reaction volumes can be miniaturized by up to a million-fold compared to conventional assays in microtitre plates. This opens up exciting prospects for the development of extremely innovative systems with many applications in the Life Sciences. The successful candidate will join a highly multidisciplinary team, with experience spanning biology, chemistry and physics.
Project
The aim of the collaborative project is to develop innovative state of the art microfluidic technologies for single-cell analyses and sorting of clinical non-small cell lung cancer (NSCLC) samples, surgical pieces and biopsies.
The postdoc will develop high-throughput single-cell targeted and whole transcriptome approaches coupled to single cell phenotypic analysis based on NGS and flow-cytometry. The combination of these technologies will allow a high-resolution analysis of the tumour microenvironment before and during immunotherapy by checkpoint inhibitors.
Requirements
We are seeking a highly motivated post-doc to work on molecular biology using droplet-based microfluidics and next generation sequencing. Requirements are a PhD in molecular biology or related fields and interest in learning how to use microfluidics systems.
Flexibility, autonomy, the ability to work in a highly multidisciplinary team and good interpersonal skills are essential.
Recruitment terms :
Starting date : August 16st 2020
Duration : 2 years
Salary : according to professional experience
Address your applications (CV + cover letter) by email to :
Prof. Andrew GRIFFITHS
Team of Biochemistry
Chemistry Biology Innovation
ESPCI Paris / CNRS
10 Rue Vauquelin
75005 Paris
job-lbc@espci.fr